Our Pipeline
Focused on making an impact in the lives of people living with cancer
Cyclacel’s pipeline of medicines aims to provide safe and effective anticancer treatment options to patients combined with the convenience of oral administration. We have retained worldwide rights for all of our prescription candidates.
Our Clinical Trials

Fadraciclib is a highly selective inhibitor of CDK2 and CDK9 currently being evaluated in midstage clinical trials in both patients with solid cancers and hematologic malignancies.

Plogosertib is a highly selective PLK-centric inhibitor currently in Phase 1 studies. Midstage clinical trials in both patients with solid cancers and hematologic malignancies are being planned.
Cyclacel’s candidates are experimental drugs under clinical investigation. They are not approved for human use at this time.

Sapacitabine (CYC682) is an orally available nucleoside analogue with a unique DDR mechanism.
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