Cyclacel has contributed to many scientific advancements.

Apr 2017

Moureau S et al., Identification of pharmacodynamic markers, sensitive target indications and potential combinations. Proc. Ann. Meeting AACR, 2017, Apr 1-5; Washington, D.C., Abstract 4178.

Dec 2016

Moureau S et al., Therapeutic potential of novel PLK1 inhibitor CYC140 in esophageal cancer and acute leukemia. 28th EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics; 2016 Nov 29–Dec 2; Munich, Germany. Abstract 355.

Nov 2012

Zheleva D et al., Parameters improving the therapeutic window of Compound 4, a potent and selective Polo-like kinase 1 inhibitor: in vitro studies. National Cancer Research Institute (NCRI) Cancer Conference 2012, Nov 4-7; Liverpool, UK. NCRI; Nov 2012. Abstract B15.

Apr 2012

Frame S et al., Potent and selective small molecule inhibitors of Polo-like kinase 1: Biological characterization. Proceedings of the 103rd Annual Meeting AACR; 2012, Mar 31-Apr 4; Chicago, Illinois. Philadelphia, PA: AACR; 2012. Abstract 2814.

Apr 2010

Hollick JJ et al., Discovery, biological characterization and oral antitumor activity of polo-like kinase 1 (Plk1) selective small molecule inhibitors. Proceedings of the 101st Annual Meeting AACR; 2010, Apr 17-21; Washington, DC, Abstract 4435.

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Paul McBarron

Executive Vice President, Chief Financial Officer & Chief Operating Officer​

Mr. McBarron has served as a director of the Company since March 2006. Mr. McBarron joined Cyclacel in January 2002 and has over 30 years of experience with pharmaceutical and biotechnology companies. He has served as a financial executive at Sterling Drug, Sanofi-Winthrop and SmithKline Beecham and, from 1996 to 2001, as a senior member of the finance team at Shire Pharmaceuticals plc, where he held the positions of Director of Corporate Finance and Group Financial Controller. He joined Shire when it was an emerging public company. He qualified as a chartered accountant with Ernst & Young and served on the Scottish Lifesciences Association Board.